Ceftiofur the United States in the 1980s for the successful development of the veterinary of the third generation cephalosporins, in 1988 the drug in the United States first listed, ceftiofur antibacterial broad spectrum antimicrobial activity strong, and the Gram Positive bacteria, anaerobes gram-negative and some are very strong antibacterial activity. Some researchers ceftiofur by thousands of veterinary clinical isolates of the pathogen antimicrobial test results showed that the antibacterial activity of the drug is one of the strongest drug, E. coli, and more killing and hemolytic Barthel Bacteria, typhoid Salmonella, Streptococcus have a strong antibacterial activity of Pseudomonas aeruginosa, Enterobacter, anaerobes also a very good role.