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Sell: Capsaicin |
| Date: |
2013-12-16 |
| Cas#: |
404-86-4 |
| Specification: |
98% |
| Price: |
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| Quantity: |
Kilogram |
| Term: |
365 |
| Note: |
Product name: Capsaicin
Assay: Capsaicin 60% 95% 98%
Molecular weight: 305.4
Molecular formula: C18H27NO3
Appearance: White acicular crystals
CAS #: 404-86-4
Capsaicin is a natural compound with pharmacological and toxicological effects, which given its hydrophobicity, can influence the structure of membranes. The interaction of capsaicin with model membranes of dipalmitoylphosphatidylcholine and dielaidoylphosphatidylethanolamine has been studied by using differential scanning calorimetry, fluorescent probe spectroscopy and 31P-nuclear magnetic resonance. Capsaicin remarkably affects the phase transition of dipalmitoylphosphatidylcholine, shifting the transition temperature to lower values, and giving rise, at relatively high capsaicin concentrations, to the appearance of two peaks in the thermogram. These peaks may correspond to separated phases as indicated by the partial phase diagram. Whereas capsaicin did not affect the fluorescence polarization of the probes diphenylhexatriene and trimethylammonium-diphenylhexatriene, it clearly affected that of the probe 2-anthroyloxystearic acid, indicating that the perturbation produced by capsaicin on the membrane would be mainly at the position where this fluorophore is located. |
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