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E3 Ligase Ligand-linker Conjugate 115

4-(1,3-Dioxolan-2-yl)phenethyl methanesulfonate

OMs-PEG2-NHAlloc-PEG2-Boc

3,8-Diazabicyclo[3.2.1]octane-4-pyrimidine-piperidine-cyclohexene-Bpin

E3 Ligase Ligand-linker Conjugate 117

3,8-Diazabicyclo[3.2.1]octane-pyrimidine-piperidine-cyclohexene-Bpin

E3 Ligase Ligand-linker Conjugate 118

FAM labled IONIS-FGFR4Rx sodium

Cy3 labled IONIS-FGFR4Rx sodium

AZD8701 sodium scrambled negative control

FAM labled AZD8701 sodium

Cy3 labled AZD8701 sodium

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