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对羟基苯甲醇 |
| CAS No.: |
623-05-2 |
| 分子式： |
C7H8O2 |
| 分子量： |
124.14 |
| 备注： |
中文名称对羟基苯甲醇中文同义词4-羟基苯甲醇;对羟基苄醇;对羟基苯甲醇;比索洛尔ALCOHOL杂质;4-羟基苄醇;对羟基苯甲醇(分析标准品);4-羟基苯甲醇,对羟基苯甲醇;天麻苷元英文名称4-Hydroxybenzylalcohol英文同义词4-hydroxyphenylMethanol;4-(Hydroxymethyl)phenol98%;4-Hydroxybenzylalcohol,(4-Hydroxyphenyl)methanol;4-Hydroxybenzylalcohol,97%25GR;Thehydroxybenzylalcohol;P-(HYDROXYMETHYL)PHENOL;P-HYDROXYBENZYLALCOHOL;RARECHEMALBD0098CAS号623-05-2分子式C7H8O2分子量124.14EINECS号210-768-0相关类别通用试剂;标准品;医药中间体;有机原料;植物提取物;有机砌块;其它含氧化合物;醇;有机无机化工;有机化工原料;有机化工原料;分析试剂标准品;中草药成分;Aromatics;Benzhydrols,Benzyl&SpecialAlcohols;AlphabeticalListings;FlavorsandFragrances;G-H;BifunctionalCrosslinkersOxygenCompounds;Alcohols;C7toC8;Linkers;PeptideSynthesis;BifunctionalCrosslinkers;合成材料中间体;化工原料;对照品-中药对照品;其它酚类;标准品-中药标准品;化学产品;成熟工艺;标准品，对照品;中药对照品;杂质对照品;化工;化工原料-1827181813;PeptideChemistry;BuildingBlocks;C7toC8;ChemicalBiology;ChemicalSynthesis;OrganicBuildingBlocks;OxygenCompounds;Pharmaceuticalintermediates;bc0001Mol文件623-05-2.mol结构式对羟基苯甲醇性质熔点114-122°C(lit.)沸点251-253°C密度1.1006(roughestimate)折射率1.5035(estimate)FEMA3987|4-HYDROXYBENZYLALCOHOL闪点251-253°C储存条件Storebelow+30°C.溶解度水中的溶解度为6.7克/升形态结晶粉末酸度系数(pKa)pK1:9.82(25°C)颜色粉色至米色气味(Odor)果香苦杏仁味香型fruity水溶解性Solubleinwater(6.7mg/mlChemicalbookat20°C),dioxane(100mg/ml),1NNaOH(50mg/ml),DMSO,andmethanol.敏感性LightSensitive/AirSensitiveJECFANumber955BRN1858967InChIKeyBVJSUAQZOZWCKN-UHFFFAOYSA-NLogP0.21CAS数据库623-05-2(CASDataBaseReference)NIST化学物质信息Benzenemethanol,4-hydroxy-(623-05-2)EPA化学物质信息4-Hydroxybenzenemethanol(623-05-2)对羟基苯甲醇用途与合成方法用途对羟基苯甲醇是加利车霉素缀合物中的合成试剂，用于治疗急性髓细胞性白血病。参与多酚氧化酶催化的酚氧化。也用于制备抗疟药。应用对羟基苯甲醇为醇类有机物，可用作有机合成中间体。生物活性4-Hydroxybenzylalcohol是广泛分布于各种植物中的酚类化合物。具有抗炎，抗氧化，抗伤害感受活性。神经保护作用。抑制肿瘤血管生成和生长。靶点HumanEndogenousMetabolite体外研究4-HydroxybenzylalcoholinhibitsproliferationofeEND2cellsandsuppressesthemigrationofeEND2cells,accompaniedbyinhibitionofactinfilamentreorganization.4-Hydroxybenzylalcoholinducesapoptoticdeathoftumorcells.体内研究4-Hydroxybenzylalcoholpossessesantiangiogenic,anti-inflammatoryandanti-nociceptiveactivitypossiblyviaitsdown-regulatingactivityonNOproduction.4-Hydroxybenzylalcohol(200mg/kg)efficientlyinhibitsgrowthandangiogenesisofdevelopingtumors.4-Hydroxybenzylalcoholamelioratesischemicinjuryinducedbytransientfocalcerebralischemiainrats,andthisneuroprotectiveeffectmaybepartlyrelatedtoattenuateapoptosispathway.化学性质可溶于甲醇、乙醇、DMSO等有机溶剂，来源于合欢皮。用途用作有机合成中间体用途有机合成中间体，可用于多肽合成 |
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