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1-[2-氟-6-(三氟甲基)苄基]-5-碘-6-甲基嘧啶-2,4(1H,3H)-二酮 |
| CAS No.: |
1150560-54-5 |
| 分子式： |
C13H9F4IN2O2 |
| 分子量： |
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| 备注： |
中文名称1-[2-氟-6-(三氟甲基)苄基]-5-碘-6-甲基嘧啶-2,4(1H,3H)-二酮中文同义词ELAGOLIX中间体;噁拉戈利中间体5;噁拉戈利钠N-5;恶拉戈利中间体;1-(2-氟-6-三氟甲基苯基)-5-碘-6-甲基脲嘧啶;1-[2-氟-6-(三氟甲基)苄基]-5-碘-6-甲基嘧啶-2,4(1H,3H)-二酮;1-[[2-氟-6-(三氟甲基)苯基]甲基]-5-碘-6-甲基-2,4(1H,3H)-嘧啶二酮;1-(2-氟-6-三氟甲基-苄基)-5-碘-6-甲基-1H-嘧啶-2,4-二酮英文名称1-[2-fluoro-6-(trifluoromethyl)benzyl]-5-iodo-6-methylpyrimidine-2,4(1H,3H)-dione英文同义词1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-5-iodo-6-methyl-2,4(1H,3H)-Pyrimidinedione;1-[2-fluoro-6-(trifluoromethyl)benzyl]-5-iodo-6-methylpyrimidine-2,4(1H,3H)-dione;elagolixintermediate5;1-{[2-fluoro-6-(trifluoromethyl)phenyl]methyl}-5-iodo-6-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione;EOS-60322;1-[[2-Fluoro-6-(trifluoromethyl)phenyl]methyl]-5-iodo-6-methyl-2,4(1H,3H)Chemicalbook-pyrimidinedione1-[[2-Fluoro-6-(trifluoromethyl)phenyl]methyl]-5-iodo-6-methyl-2,4(1H,3H)-pyrimidinedione;1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-5-iodo-6-methylpyrimidine-2,4-dione;1-[[2-Fluoro-6-(trifluoromethyl)phenyl]methyl]-5-iodo-6-methyl-2-2,4(1H,3H)-pyrimidinedioneCAS号1150560-54-5分子式C13H9F4IN2O2分子量428.12EINECS号687-893-6相关类别噁拉戈利钠Mol文件1150560-54-5.mol结构式1-[2-氟-6-(三氟甲基)苄基]-5-碘-6-甲基嘧啶-2,4(1H,3H)-二酮性质熔点>190oC(dec.)密度1.88±0.1g/cm3(Predicted)储存条件-20°CFreezer,Underinertatmosphere溶解度可溶于氯仿（轻微）、DMSO（轻微）、甲醇（轻微、加热）酸度系数(pKa)8.04±0.40(Predicted)形态固体颜色白色至类白色LogP21-[2-氟-6-(三氟甲基)苄基]-5-碘-6-甲基嘧啶-2,4(1H,3H)-二酮用途与合成方法用途1-[2-氟-6-(三氟甲基)苄基]-5-碘-6-甲基嘧啶-2,4(1H,3H)-二酮是ELAGOLIX的合成中间体，Elagolix是用于治疗子宫内膜异位症的促性腺激素释放激素拮抗剂(GnRH)。 |
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