|
|
奥替尼啶盐酸盐 |
| CAS No.: |
70775-75-6 |
| 分子式： |
C36H64Cl2N4 |
| 分子量： |
623.82616 |
| 备注： |
中文名称奥替尼啶盐酸盐中文同义词奥替尼啶奥克太啶(双盐酸盐);奥克太啶盐酸盐;奥替尼啶盐酸盐;奥替尼啶二盐酸盐;奥替尼啶杂质;奥替尼啶,奥克太啶;奥替尼定盐酸盐;盐酸奥替尼啶英文名称Octenidinedihydrochloride英文同义词N,N’-(1,10-Decanediyldi-1(4H)-pyridinyl-4-ylidene)bis(1-octanamine)dihydrochloride;N,N’-(decane-1,10-diyldi-1(4H)-pyridyl-4-ylidene)bis(octylammonium)dichloride;Octenidinehydrochloride;OCTENIDINEDIHYDROCHLORIDE;N,N’-(1,10-Decanediyldi-1(4H)-pyridinyl-4-ylidene)bis-1-octanaMineHydrochloride;N’-(decane-1,10-diyldi-1(4H)-pyridyl-4-ylidene)bis(octylaMMoniuM)dichloride;1-OctanaMine,N,N’-(1,10-decanediyldi-1(4H)-pyridinyl-4-ylidene)bis-,hydrochloride(1:2);ocenidinedihydrochlorideCAS号70775-75-6分子式C36H64Cl2N4分子量623.82616EINECS号274-861-8相关类别原料药;医药原料;原料药;化妆品原料;抗菌;新型抗菌;医药原料药;合成;医药抗菌剂;医用原料;医药化工原料;化工原料;化工中间体;Amines;Heterocycles;Intermediates&FineChemicals;Pharmaceuticals;原料;其他原料;化学试剂;化工品Mol文件70775-75-6.mol结构式奥替尼啶盐酸盐性质熔点215-217℃密度1.046[at20℃]蒸气压0Paat25℃储存条件Keepindarkplace,InertatmospheChemicalbookre,Roomtemperature溶解度溶于二甲基亚砜和甲醇。形态固体颜色白色至类白色水溶解性14.2g/Lat20℃Merck14,6754稳定性吸湿性InChIKeySMGTYJPMKXNQFY-UHFFFAOYSA-NSMILES[N+]1(CCCCCCCCCC[N+]2C=CC(NCCCCCCCC)=CC=2)=CC=C(NCCCCCCCC)C=C1.[Cl-].[Cl-]LogP1.5at23℃奥替尼啶盐酸盐用途与合成方法生物活性Octenidine是一种阳离子型表面活性剂，对革兰氏阳性和阴性的细菌具有活性。体外研究Octenidineconcentrationsoflessthan1.5μM(0.94μg/mL)causesagreaterthan99%reductionoftestedmicrobialpopulationwithin15min.Staphylococcusepidermidisisthemostsusceptibleofthetestorganisms,andE.coliandC.albicansaretheleastsusceptible.体内研究Theantimicrobialactivityofoctenidinehydrochloride(OCT)ismaintainedwhenappliedtotheskinofthehandsandfeetofcynomolgusmonkeys.Aqueousoctenidine,ataconcentrationof0.2to1.6%reducesresidentmicroflorapopulationsfrom90to99.98%.Asignificantreductioninplaquescoreisobservedonthebuccaltoothsurfacesafterdailytopicalapplicationof1%solutionsofoctenidineandchlorhexidinefor7d;octenidineismoreeffectivethanchlorhexidine. |
| 结构式： |
 |
 |
|
声明：以上信息未经本网证实,仅供参考,华夏化工网不承担任何风险责任. |
|
