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4-[2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)ethynyl)-benzoicacid |
| CAS No.: |
104561-41-3 |
| 分子式： |
C23H24O2 |
| 分子量： |
332.00 |
| 备注： |
中文名称4-[2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)ethynyl)-benzoicacid中文同义词化合物EC23;4-[2-(5,5,8,8-TETRAMETHYL-6,7-DIHYDRONAPHTHALEN-2-YL)ETHYNYL]BENZOICACID;4-((5,5,8,8-四甲基-5,6,7,8-四氢萘-2-基)炔基)苯甲酸;EC-23,光稳定的合成类维生素A;4-((5,5,8,8-四甲基-5,6,7,8-四氢萘-2-基)乙炔基)苯甲酸英文名称4-[2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)ethynyl)-benzoicacid英文同义词4-[2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)ethynyl)-benzoicacid;EC23;OQVLOWLEEHYBJH-UHFFFAOYSA-N;BASF-46928;Benzoicacid,4-[2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)ethynyl]-;Inhibitor,EC-23,BASF46928,EC23,EC23,AGN-190205,BASF46928,AGN190205,inhibit;4-((5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethynyl)ChemicalbookbenzoicacidCAS号104561-41-3分子式C23H24O2分子量332.44EINECS号相关类别Mol文件104561-41-3.mol结构式4-[2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)ethynyl)-benzoicacid性质熔点254-256°C(Solv:acetonitrile(75-05-8))沸点484.7±45.0°C(Predicted)密度1.15±0.1g/cm3(Predicted)储存条件Storeat+4°C溶解度DMF：5mg/mL；DMSO：5mg/mL；DMSO:PBS(pH7.2)(1:1)：0.5mg/ml；乙醇：1mg/mL酸度系数(pKa)4.10±0.10(Predicted)形态白色至灰白色冻干无定形固体。颜色米白色至浅黄色4-[2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)ethynyl)-benzoicacid用途与合成方法生物活性EC23(AGN190205)是稳定的合成类视黄醇类似物，可诱导神经元分化。体外研究EC23(AGN190205)inducesneuraldifferentiationaccompanyingbyelevatedlevelsofstathminandprofilin-1.EC23inducestheexpressionofknowncellularretinoidbindingproteinsintheTERA2.cl.SP12cellline. |
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