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D-蛋氨酸 |
| CAS No.: |
348-67-4 |
| 分子式： |
C5H11NO2S |
| 分子量： |
149.21 |
| 备注： |
中文名称D-蛋氨酸中文同义词D-2-氨基-4-甲硫基丁酸;D-蛋氨酸;D-甲硫氨酸(D-蛋氨酸);D-甲硫氨酸/D-蛋氨酸/D-2-氨基-4-甲硫基丁酸/D-甲硫基丁氨酸;D-METHIONINED-蛋氨酸;D-甲硫氨酸,D-2-氨基-4-甲硫基丁酸;D-蛋氨酸,99%;D-蛋氨酸/D-甲硫氨酸英文名称D-Methionine英文同义词D-2-AMINO-4-[METHYLTHIO]BUTANOICACID;d-2-amino-4-(methylthio)butyricacid;H-D-MET-OH;D-LOBAMINE;D-METHIONINE;D-BANTHIONINE;(R)-2-AMINO-4-(METHYLMERCAPTO)BUTYRICACID;(2R)-2-Amino-4-methylsulfanylbutanoicacidCAS号348-67-4分子式C5H11NO2S分子量149.21EINECS号206-483-6相关类别D系列氨基酸;氨基酸及其衍生物;生化试剂;精细化学品;氨基酸;其他生化试剂;保护氨基酸;非天然氨基酸;医药原料;标准品;氨基酸AminoAcid;氨基酸和衍生物;氨基酸类;PROTECTEDAMINOACID&PEPTIDES;保护氨基酸及多肽类产品;Methionine[Met,M];化学生物学;天然氨基酸极其衍生物;氨基酸衍生物;营养增补剂;化学试剂;中药对照品;对照品;生化试剂-氨基酸类;原料药API;原料;生化试剂-氨基酸;D-氨基酸;有机化工原料;有机中间体;化工原料;通用生化试剂-氨基酸;对照品;AminoACIDSSERIES;AminoAcidDerivatives;AminoAcidsandDerivatives;AminoAcidsandDerivatives;AminoAcidsMol文件348-67-4.mol结构式D-蛋氨酸性质熔点273-275°C比旋光度-24º(c=8,6NHCl)沸点306.9±37.0°C(Predicted)密度1.113(estimate)折射率1.5216(estimate)储存条件Sealedindry,RoomTemperature溶解度53g/l（20°C）酸度系数(pKa)2.23±0.10(Predicted)形态粉末颜色白色至类白色水溶解性53g/L(20ºC)Merck14,5975BRN1722293稳定性稳定的。与强氧化剂不相容。LogP0.370(Chemicalbookest)CAS数据库348-67-4(CASDataBaseReference)NIST化学物质信息D-(l)-Methionine(348-67-4)EPA化学物质信息D-Methionine(348-67-4)D-蛋氨酸用途与合成方法生物活性Methionine(MRX-1024;D-Methionine)是一种有效的化学保护剂，它还可以通过激活GABAA受体来抑制神经元活性。靶点GABAAreceptor体外研究TheincubationofhumanplasmawithMethionine(D-methionine)andCPleadstotheformationofaPt-D-methioninecomplexindependentoftheorderofaddition.Inplasma,anearlyCPhydrolysisproductreactswithMethioninetoforma1:1complexthatisfollowedbytheformationofa2:1compoundatalatertimepoint.TheformationofthesePt-D-methioninespeciesplaysanimportantroleintheprocessesbywhichMethionineprotectsmammalianorganismsagainstCP-inducedtoxicities.体内研究WhenMethionine(D-methionine)isadministeredalongwithcisplatinthecelldensityis0.8±0.070(SEM),significantlylargerthaninratstreatedwithonlycisplatin(P<0.01)whilenotsignificantlydifferentfromcontrolsorfromanimalstreatedonlywithD-methionine(P>0.05).WhenMethionineisadministeredalonetheaveragecelldensityis0.95±0.099(SEM)andnotsignificantlydifferentfromcontrols(P>0.05).化学性质D-蛋氨酸为白色结晶。溶于水、稀酸及碱，极微溶于醇，不溶于醚。用途用作生化试剂。用途用于生化研究和营养增补剂 |
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