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4-(3-氯-4-氟苯氨基)-7-甲氧基喹唑啉-6-醇 |
| CAS No.: |
184475-71-6 |
| 分子式： |
C15H11ClFN3O2 |
| 分子量： |
319.72 |
| 备注： |
中文名称4-(3-氯-4-氟苯氨基)-7-甲氧基喹唑啉-6-醇中文同义词O-去吗啉丙基吉非替尼;3-氯-4-氟苯氨基)-7-甲氧基喹唑啉-6-醇;4-(3-氯-4-氟苯胺)-7-甲氧基-喹唑啉-6;吉非水解物;吉非水解物4-(3-氯-4-氟苯氨基)-7-甲氧基喹唑啉-6-醇;4-(3-氯-4-氟苯胺)-6-羟基-7-甲氧基喹唑啉;4-(3-氯-4-氟苯胺基)-6-羟基-7-甲氧基喹唑啉;4-[(3-氯-4-氟苯基)氨基]-7-甲氧基-6-喹唑啉醇英文名称O-DesmorpholinopropylGefitinib英文同义词FAAH-IN-2;4-(3-Chloro-4-fluorophenylamino)-6-hydroxy-7-methoxyquinazoline;4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinol;O-DesmorpholinopropylGefitinib;4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol;GefitinibinterMediateVII;4-(3-Chlor-4-fluorophenylamino)-7-methoxyquinazolin-6-ol;GefitinChemicalbookibIntermediate1CAS号184475-71-6分子式C15H11ClFN3O2分子量319.72EINECS号1806241-263-5相关类别医药中间体;吉非替尼;抗肿瘤;中间体;医药原料;Gefitinib;VariousMetabolitesandImpurities;Intermediates&FineChemicals;Metabolites&Impurities;PharmaceuticalsMol文件184475-71-6.mol结构式4-(3-氯-4-氟苯氨基)-7-甲氧基喹唑啉-6-醇性质熔点>260°C(dec.)沸点478.8±45.0°C(Predicted)密度1.489±0.06g/cm3(Predicted)储存条件Keepindarkplace,Inertatmosphere,Storeinfreezer,under-20°C溶解度可溶于DMSO（轻微）、甲醇（非常轻微，加热）酸度系数(pKa)8.18±0.40(Predicted)形态固体颜色浅米色至米色4-(3-氯-4-氟苯氨基)-7-甲氧基喹唑啉-6-醇用途与合成方法生物活性FAAH-IN-2(O-DesmorpholinopropylGefitinib)是摘自专利WO/2008/100977A2中的FAAH抑制剂。用途吉非替尼中间体 |
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